The Best 6-Minute Effort (B6ME)™ is a novel outcome assessment that helps researchers achieve a comprehensive picture of how disease impacts patient functioning in their real-world environment. It parallels the accepted 6MWT, using wearable sensors to track the peak 6-minute effort within a calendar day. Real-world movement and mobility-related information collected over weeks, months, or years, significantly advance our understanding of disease expression and therapeutic outcomes.
B6ME is a sustained assessment of disease activity, providing insight into how patients function during their everyday activities. Data are collected within an FDA regulated framework using medical-grade, wrist-worn, or other fit-for-purpose wearable devices.
Using a wearable sensor, we can derive more detailed measures of movement and mobility beyond what is possible from in-clinic standardized assessments. By identifying a best six-minute effort, additional digital measures of heart rate, respiration rate, steps, cadence, stride length, and stride velocity may be provided in this defined context.
