Articles and Insights About Wearables for Clinical Trials

Articles by Jen Blankenship, PhD

Jen Blankenship, PhD

Jen Blankenship, PhD, is a clinical and translational scientist with a deep interest in wearable technology (e.g., continuous glucose monitors and accelerometers).

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Recent Articles


Patient-Centric Digital Endpoints of Function for AD Research

 Jen Blankenship, PhD

At the ISCTM 20th Annual Scientific Meeting, Senior Research Scientist Jen Blankenship, PhD, presented our ongoing work to understand patient perspectives on how mild AD impacts their daily life and function and identify the meaningful aspects of health that are measurable with low-burden wearable actigraphy sensors. Download the poster and read the abstract below.

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Why You Should Include Digital Endpoints in Clinical Trials

 Jen Blankenship, PhD

See how research teams can start using wearables to identify novel digital biomarkers to efficiently generate real-world patient evidence in clinical trials.

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The Importance of Patients as Partners in Alzheimer's Disease Research

 Jen Blankenship, PhD

Jen Blankenship, PhD, Senior Research Scientist, moderated a lively discussion with Shelby Bachman, PhD, Research Scientist, and an expert panel about the promise of Digital health technologies (DHTs) like smartphones and wearable sensors to advancing drug development and discovery in neurodegenerative diseases, particularly Alzheimer’s disease.

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VivoSense Study to Develop Digital Measures of Function for AD

 Jen Blankenship, PhD

At the a2 National Symposium: Empowering Innovation in AI/Tech + Aging, Senior Research Scientist Jen Blankenship, PhD, presented our ongoing work with the Center for Human Health and Performance at the University of Massachusetts Amherst to develop digital clinical measures that capture how patients with Alzheimer’s disease function in their real-world environments. 

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Opportunities for Real-World Measures in Alzheimer's Research

 Jen Blankenship, PhD

Alzheimer’s disease (AD) is a devastating neurodegenerative disease that progresses to impact every dimension of a patient’s life. With no cure and limited options to manage symptoms, research is underway to develop drugs that impact the most burdensome aspects of AD: memory problems and the ability to function independently.

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Measuring Physical Function and Mobility in Real World Settings

 Jen Blankenship, PhD

Physical function and mobility are relevant to virtually all clinical indications and are significant determinants of an individual’s quality of life. Because of this, function and mobility are often assessed in clinical trials using subjective questionnaires or in-clinic performance tests, but these assessments may not reflect a patient’s lived experience. Wearable sensors provide an opportunity to move assessments of function into the real world to measure how patients feel and function in their everyday environments.

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Understanding Neurodegenerative Diseases with Wearable Sensors

 Jen Blankenship, PhD

Millions of people across the globe struggle with neurodegenerative diseases every day. Neurodegenerative diseases are characterized by a breakdown of the central and peripheral nervous systems and cause progressive deterioration of a normally functioning human body. However, a significant challenge in studying neurodegenerative diseases is that direct measurements of neurological systems are invasive and expensive.

Wearable sensors can be used to understand disease progression and manifestation by measuring physical symptoms and physiological outcomes.

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