Articles and Insights About Wearables for Clinical Trials

On June 7th, 2023, Robert Wright, PhD, Senior Research Scientist at VivoSense, and Jana Von Hehn, PhD, CSO at Rett Syndrome Research Trust, presented at the Digital Health Innovation Summit, a forum to learn from the best about top trends in the industry. Their presentation, Developing Patient-Centric Real-World Digital Clinical Measures for Rett Syndrome, summarized years of collaborative work implementing digital health technologies in complex research programs.

VivoSense announces an expansion of our collaboration with the Rett Syndrome Research Trust (RSRT). Building on the success of our previous collaborations, VivoSense and RSRT will continue to support the development of treatments for Rett Syndrome (RTT) by qualifying objective digital outcome measures of breathing problems for use in RTT trials.

VivoSense recognizes Rare Disease Day by minding the importance of discovering new advancements in research and clinical trials to care for those with rare diseases. There are approximately 30 million Americans living with rare diseases today, and research into new therapies is imperative for these patients.

In this video, Dudley Tabakin, VivoSense CEO, shares an example of how rare disease researchers can use wearable sensors to develop digital clinical measures to improve patient outcomes. He discusses our approach to developing outcome measures from ECG Derived Respiration (EDR) to discover novel respiratory endpoints for Rett Syndrome, working with Rett Syndrome Research Trust.

Image Source: RSRT, Randol Family

VivoSense announces a series of new collaborations with the Rett Syndrome Research Trust (RSRT) to develop digital biomarkers that better assess the symptoms of Rett syndrome, focusing on autonomic dysfunction and other difficult-to-evaluate symptoms. The goal in developing these digital biomarkers is to better quantify and understand symptom impact on everyday life and to assess new treatments accurately.

Rett syndrome (RTT) is a neurodevelopmental disease that results in neurological symptoms involving respiratory dysfunction. Breathing abnormalities are essential criteria for the diagnosis of RTT and include erratic respiratory rhythms and life threatening apneas. These respiratory symptoms are more severe during wakefulness than sleep.