Respiratory abnormalities characterize a variety of disorders. In addition to physical disorders, ventilation is profoundly affected by mental and psychophysiological states, including stress, anxiety, and panic disorder.
The measurement of respiratory outcomes in the real-world requires careful artifact management. VivoSense ensures high-quality respiratory data are captured via proper protocol design, signal processing, and data analysis procedures.
Thoraco-Abdominal Respiration - Dual-band respiratory inductance plethysmography (RP) sensors are the gold standard for continuous, unobtrusive respiratory monitoring. They are widely used in clinical and research settings, and particularly in polysomnography (sleep studies). Thoracic and abdominal bands allow measurements of both breathing compartments, providing accurate volume and phase relation measurements in addition to simple respiration metrics of rate and timing.
ECG Derived Respiration (EDR) – EDR allows for continuous measurement of respiration rates and timing and has been analytically validated during sleep. Long term monitoring of transient respiratory events is possible while simultaneously enabling ECG measures to be used in a clinical endpoint. E.g., EDR, and HR.
PPG – PPG may be used to determine resting pulse rate and derive continuous measures of respiratory rate. PPG may also be used to assess decompensation via derived SpO2.
Audio – Audio recordings from wearable or app-enabled devices are used to identify cough events. EMG recordings and or patient-reported outcomes (ePRO) of frequency and intensity can enhance cough count.